UBE2K anticorps (Middle Region)

N° du produit ABIN2787511

Cet anticorps anti-UBE2K est un anticorps Lapin Polyclonal détectant UBE2K dans WB. Adapté pour Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Boeuf (Vache), Chévre, Cheval, Lapin et Cobaye.

Aperçu rapide pour UBE2K anticorps (Middle Region) (ABIN2787511)

Antigène: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Boeuf (Vache), Chévre, Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2K est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-UBE2K anticorps

Épitope: Middle Region

Séquence: TVLLSLQALL AAAEPDDPQD AVVANQYKQN PEMFKQTARL WAHVYAGAPV

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against UBE2K. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human UBE2K

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 200 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur UBE2K

Antigène: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Autre désignation: UBE2K

Sujet: UBE2K belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.
Alias Symbols: DKFZp564C1216, DKFZp686J24237, E2-25K, HIP2, HYPG, LIG, UBC1
Protein Interaction Partner: DDI1, DTX3, MIPOL1, TRIM39, ANAPC11, RNF138, SIAH1, RNF5, REL, FZR1, UBC, UBA1, MARCH7, AMFR, TP53, MDM2, BAG3, PRRG4, IQCB1, HTT, CDC6, WDR1, TYMS, TXN, TXNDC17, WDR61, ITCH, NEDD4L, WWP2, NXF1, NUB1, PIAS4, CASP12, SUMO1, SUMO2, DIABLO, UBE2I, CCNB1, BR
Protein Size: 200

Poids moléculaire: 22 kDa

ID gène: 3093

NCBI Accession: NM_005339, NP_005330

UniProt: P61086